Search results for "T2* technique"
showing 10 items of 208 documents
Artisti, "artistucoli" e "buoni lavoranti": Francesco Carradori e la razionalizzazione dei processi operativi nell’«Istruzione elementare per gli stu…
2022
Francesco Carradori's treatise «Istruzione elementare per gli studiosi della scultura» (1802) codifies the organization and working process within a sculpture workshop in such an exemplary manner that it is an indispensable source for understanding the marble industry in the 19th century. The author analyses Carradori's text both through its Renaissance and Baroque sources (Vasari, Cellini, Boselli) and through encyclopaedic repertories (Baldinucci, Félibien, de Jaucourt, Falconet, Levesque) and then proposes a comparison with the similar attempt by the Prussian sculptor Johann Gottfried Schadow, whose essay «Die Werkstätte des Bildhauers» (1802) similarly narrates the work processes, but u…
Users’ Preferences for Designing Spaces under Urban Bridges as Vital Urban Spaces
2018
Today’s fast-paced urbanization process has caused many problems in urban development. Therefore, urban space is slowly losing its nature and disappearing due to the speed of rapid urban development. Trying to keep up with the modern era’s prevalent epoch of roads and bridges, urban policies in Iran have focused on developing road networks in recent years. Thus numerous elevated structures, urban highways and bridges are used to connect the urban fabric of the country’s cities, enabling the smooth transition of traffic in its cities. Although many view urban highways merely as tools for mobility; it is true that they influence on urban structure and the communities that they interconnect. H…
Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR
2014
Solid tumours are exposed to microenvironmental factors such as hypoxia that normally inhibit cell growth. However, tumour cells are capable of counteracting these signals through mechanisms that are largely unknown. Here we show that the prolyl hydroxylase PHD3 restrains tumour growth in response to microenvironmental cues through the control of EGFR. PHD3 silencing in human gliomas or genetic deletion in a murine high-grade astrocytoma model markedly promotes tumour growth and the ability of tumours to continue growing under unfavourable conditions. The growth-suppressive function of PHD3 is independent of the established PHD3 targets HIF and NF-κB and its hydroxylase activity. Instead, l…
Proliferative response of cells of the dentogingival junction to mechanical stimulation
2001
SUMMARY The aim of this research was to study the proliferative response of junctional epithelium (JE) and gingival connective tissue (GCT) to mechanical stimulation in vivo with regard to the potential occurrence of apical migration of JE and loss of GCT attachment during orthodontic tooth movement. Elastic bands were inserted between the maxillary first and second molars of male rats aged 8 weeks, which were pulse-labelled with 3 H-thymidine and subsequently killed in groups, together with labelled control animals (a total of 98 rats) after periods of 1‐168 hours. Autoradiographs were prepared from plastic mesiodistal sections, and parameters of cell proliferation for JE and GCT of the pa…
Testing the use of an image-based technique to measure gully erosion at Sparacia experimental area
2017
The first part of this investigation was aimed at testing the use of a three‐dimensional (3D) digital terrain model and a quasi‐tridimensional (2.5D) digital elevation model obtained by a large series of oblique images of eroded channels taken from consumer un‐calibrated and non‐metric cameras. For two closed earth channels having a different sinuosity, the ground measurement of some cross sections by a profilometer (P) was carried out and their real volume was also measured. The comparison among the three methods (3D, 2.5D, and P) pointed out that a limited underestimation of the total volume always occurs and that the 3D method is characterized by the minimum difference between measured a…
Les vies étudiantes : tendances et inégalités
2016
National audience; On recense aujourd'hui plus de 2,4 millions d'étudiants en France. Une population dont les effectifs ne cessent de croître et qui se révèle être de plus en plus diversifiée. Se référer à « l'étudiant moyen » n'a donc pas plus de sens aujourd'hui qu'il n'en avait lors de la mise en place de la première enquête Conditions de vie des étudiants en 1994. Il en est de même de la vie étudiante qu'il est difficile de réduire à quelques clichés. Le seul fait d'être étudiant est loin d'homogénéiser les conditions de vie d'un public aux caractéristiques, aux expériences et aux attentes de plus en plus diversifiées. Le sexe, l'âge, la formation suivie, le parcours antérieur, la situa…
Coupled variable selection for regression modeling of complex treatment patterns in a clinical cancer registry.
2013
For determining a manageable set of covariates potentially influential with respect to a time-to-event endpoint, Cox proportional hazards models can be combined with variable selection techniques, such as stepwise forward selection or backward elimination based on p-values, or regularized regression techniques such as component-wise boosting. Cox regression models have also been adapted for dealing with more complex event patterns, for example, for competing risks settings with separate, cause-specific hazard models for each event type, or for determining the prognostic effect pattern of a variable over different landmark times, with one conditional survival model for each landmark. Motivat…
Embracing iterations in Quantum software: a vision
2022
In today’s software engineering, iterations, affordable en masse, form an important part of just about any system. However, not all computing resources are cheap to consume. In High-Performance (HPC) and Quantum Computing (QC), executions can consume considerable amounts of energy and time, which is reserved and used even if the very first steps in the process fail. This means that developers must assume a different attitude towards programming, and aim at error-free software before its execution. This is com monly facilitated using simulators, which are commonplace for both HPC and QC. However the fashion developers advance from one tool to another is ad-hoc, with no established software e…
Immunoaffinity purification and characterization of mitochondrial membrane-bound D-3-hydroxybutyrate dehydrogenase from Jaculus orientalis.
2008
Abstract Background The interconversion of two important energy metabolites, 3-hydroxybutyrate and acetoacetate (the major ketone bodies), is catalyzed by D-3-hydroxybutyrate dehydrogenase (BDH1: EC 1.1.1.30), a NAD+-dependent enzyme. The eukaryotic enzyme is bound to the mitochondrial inner membrane and harbors a unique lecithin-dependent activity. Here, we report an advanced purification method of the mammalian BDH applied to the liver enzyme from jerboa (Jaculus orientalis), a hibernating rodent adapted to extreme diet and environmental conditions. Results Purifying BDH from jerboa liver overcomes its low specific activity in mitochondria for further biochemical characterization of the e…
Weaning Premature Infants from Nasal Continuous Positive Airway Pressure - Current Practice and Scientific Evidence.
2017
Abstract Objective In the past decade, a number of trials have been conducted to determine the optimal strategy of weaning premature infants from nasal continuous airway pressure (nCPAP). However, a paucity of information exists on how weaning is actually performed in clinical routine. Aim of this study was to investigate the current practice of weaning premature infants from nCPAP in Germany. Methods An online survey was performed in German tertiary care neonatal units. Results All 160 German tertiary care units were contacted. Replies were retrieved from 85/160 (53%) units, of which 83/160 (52%) completed the questionnaire. 66/83 (80%) respondents indicated to wean without the use of form…